There are probably differences to caffeine levels and amounts of other chemical compounds present in the coffee, depending on its maturity, roast-level and environmental factors, such as the soil in which the plant has grown. Those affect the taste and potency, but also probably the adverse effects. Personally, a cup or two of coffee isn't a killer for me, but a glass of Coke, energy drink (yuck) or orange juice (due to its acidity) is. For some reason black tea seems to irritate my bladder more than coffee. Green tea's ok.
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