Medicine that might help reduce IBD diarrhea

[optimist]

There is an antidepressant that might be helpful to IBD diarrhea.
The active ingredient is called trimipramin. 20-50 mg in the evening.
The side effects are not too bad. Preliminary tests are positive.
It works by calming down the nerves in the intestines.
Maybe this information would be helpful.

[B Brian]

While not IBD for me, I can attest to an antidepressant helping to quite literally calm down nerves in general.

I take just 5mg amitriptyaline to calm my neurogenic dyssenergya cough (chronic cough caused by overly sensitive nerves in the throat). It's amazing how well it works too.